Customization: | Available |
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Grade: | Food, Cosmetic, Pharm |
MOQ: | 1kg |
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Product Name | Rapamycin |
CAS Number | 53123-88-9 |
Appearance | White powder |
Molecular formula | C51H79NO13 |
Molecular Weight | 914.172 |
Keywords | Rapamycin;Sirolimus |
Shelf Life | 24 months when properly stored |
Storage | Keep in a cool, dry, dark location |
Anti-cancer properties: Rapamycin has shown promise as a potential anti-cancer agent. It can inhibit the growth of tumor cells by blocking mTOR signaling pathways involved in cell division and angiogenesis (the formation of new blood vessels that supply nutrients to tumors).
Anti-aging properties: Rapamycin has gained attention for its potential to extend lifespan and improve healthspan in various organisms, including yeast, worms, flies, and mice. It is believed to act on cellular and molecular pathways associated with aging and age-related diseases.
Treatment of certain rare genetic disorders: Rapamycin has been used to manage certain rare genetic disorders like tuberous sclerosis complex (TSC) and lymphangioleiomyomatosis (LAM). These conditions involve the abnormal growth of noncancerous tumors, and rapamycin can help inhibit their progression.
Cardiac applications: Rapamycin-eluting stents are commonly used in interventional cardiology to prevent blockage of arteries after angioplasty. The drug coating on the stent helps inhibit the growth of scar tissue that can lead to restenosis.
Rapamycin is a triene macrolide antibiotic, which demonstrates anti-fungal, anti-inflammatory, anti-tumor and immunosuppressive properties. Rapamycin has been shown to block T-cell activation and proliferation, as well as, the activation of p70 S6 kinase and exhibits strong binding to FK-506 binding proteins.
Rapamycin also inhibits the activity of the protein, mTOR, (mammalian target of rapamycin) which functions in a signaling pathway to promote tumor growth. Rapamycin binds to a receptor protein (FKBP12) and the rapamycin/FKB12 complex then binds to mTOR and prevents interaction of mTOR with target proteins in this signaling pathway.
1.Preferentially DHL, FedEX or TNT for quantity less than 50kg, air shipping for 100kg above, sea shipping for quantity over 500kg.
2.For customers from Russia,Mexico,Turkey,Solvenia,etc,before placing an order,please kindly confirm if you can make clearance when goods reach your customs.Shipping Terms | ||
By Express | By Air | By Sea |
Suitable for under 100kg Fast:3-4 days High cost Door to door service Easy to pick up the goods |
Suitable for more than 100kg Fast:3-4 days High cost Airport to airport Professional broker needed |
Suitable for more than 500kg Slow:15-30 days Low cost Port to port Professional broker needed |
Hefei Yili Import and Export co.,ltd was established in Hefei,Anhui. It is specialized in manufacture plant extract, API and chemicals raw material powder, food additives and oil,which are applied to skin care, healthcare and cosmetic products.We will uphold honesty and pragmatic, innovative and enterprising service purposes, and provide a variety of quality services to our customers at abroad. It aims at supplying good product and comfort service. The strict quality control is to meet the customer's requirement, to get a highly praised and to be high quality supplier. If you have any question, or need samples, please feel free to contact us.